11. Science. 1923-1994.
This section has been divided into fifteen thematic sub-sections, which, when taken
as a whole, reflect the extraordinary breadth of Linus Pauling's scientific biography.
Boxes in the Science section typically hold manuscripts, research notes, correspondence,
figures, experimental data, non-Pauling reprints and other scientific research materials.
Generally speaking, materials have been arranged and cataloged according to research
topic. However, two sub-sections reflect the institutional architecture either supporting
or directing Pauling's work during specific periods of his life. For example, the
bulk of the collection's holdings concerning Pauling's relationship with the American
Chemical Society have been cataloged under the rubric "Scientific, Research and Grant-Funding
Institutions." A similar approach has been taken with much of Pauling's work sponsored
by the Guggenheim Foundation, Rockefeller Foundation, Ford Foundation, etc.
221 boxes
7. The Structure of Antibodies and Antigens; the Nature of Serological Reactions.
Boxes 7.001 - 7.004 (Page: 1 - 4)
7.001.
Materials re: Antibody and Antigen Research; the Nature of Serological Reactions,
1940-1947, 1950-1952, 1973, 1986.
1.1.
Correspondence re: Antibody and Antigen research; the nature of serological reactions,
1940-1947, 1973.
1.2.
Manuscript Notes: "Theory of Precipitation Reactions", September 21, 1941.
1.3.
Manuscript Notes, Calculations: "Antigen-Antibody Interactions" and "Antigen-Antibody-Haptene
Interaction", December 24 - January 20, 1942, December 1941 - January 1942 [?], . [LP and Verner Schomaker].
1.4.
Manuscript Notes, Calculations: Hapten Inhibition for Heterogeneous Antiserum, July-August, 1943. [LP and David Pressman].
1.5.
Assorted Notes, Calculations, Drawings and Memoranda re: Antigen and Antibody research,
1940-1944. [LP and David Pressman].
1.6.
Manuscript Notes, Abstract re: "Immunological Reactions between Films of Antigen and
Antibody Molecules", by Alexandre Rothen. J. Biol. Ch. vol. 168, (1947): 75-97.
1.7.
Manuscript Notes, Calculations: Van der Waals Forces in Serology, [specific focus
on benzoic acids] No Date [1940s].
1.8.
Typescript, Correspondence, Notes: The Non-Specific Precipitation of Dyes and Proteins, by J. L. Morrison and Linus Pauling, January 1950 - October 1952.
1.9.
Manuscript Notes: "Theory of Electrophoretic Patterns of Antigen and Heterogeneous
Antibody", February 5, 1950; Notes to Self re: antibodies, July 3, 1950 and August 4, 1950.
1.10.
Correspondence, Articles, re: Immunochemistry and monoclonal antibodies, 1986.
7.002.
Glass Slides: "Pictures of Antibodies", prepared for the First International Poliomyelitis
Conference, New York, July 12-17, 1948.
2.1.
Glass Slides: "Pictures of Antibodies", prepared for the First International Poliomyelitis
Conference, New York, July 12-17, 1948. [two large plates containing three images each].
7.003.
Non-Pauling Materials re: LP Antibody and Antigen Research; the Nature of Serological
Reactions, No Date.
3.1.
Non-Pauling Offprint: "A History of Theories of Antibody Formation", Arthur M. Silverstein,
Cellular Immunology, 91: 263-283 (1985).
3.2.
Non-Pauling Offprint: "Molecular biology and Pauling's immunochemistry: a neglected
dimension", Hist. Phil. Life Sci., 11: 211-219 (1989).
3.3.
Non-Pauling Offprint: "The Tools of the Discipline: Standards, Models, and Measures
in the Affinity/Avidity Controversy in Immunology," Peter Keating, Alberto Cambrosio
and Michael Mackenzie, in The Right Tools for the Job: At Work in Twentieth-Century Life Sciences, Princeton University Press, 1992.
3.4.
Non-Pauling Typescript: "How Immunologists Argue with Images: Pauling's Theory of
Antibody Formation", Alberto Cambrosio, Daniel Jacobi and Peter Keating, 2002.
7.004.
Collected Literature References and Summaries re: Antibody and Antigen Research; the
Nature of Serological Reactions.
4.1.
Collected Literature References and Summaries re: Antibody and Antigen Research; the
Nature of Serological Reactions.
